Technology Helps Parkinson's Disease Patient Regain Independence

Deep Brain Stimulation Stops Disease Tremors

• By Suzanna Cisneros
• May 1, 2018

Errin Luton was 30 years old when he began to notice stiffness in his hands and a small twitch in his fingers. A police officer in Dallas at the time, he later noticed the twitching began to progress from his right hand to the rest of his body. In 2007, Luton was diagnosed with early onset Parkinson’s disease. Ten years into his disease, he could not have imagined that the flip of a switch would help control his tremors
 
“I was devastated when I was diagnosed,” Luton said. “I had no clue what Parkinson’s disease was.”
 
The National Institute of Neurological Disorders and Stroke states Parkinson's disease belongs to a group of conditions called motor system disorders. The four primary symptoms are tremors or trembling in hands, arms and legs; stiffness of the limbs and trunk; slowness of movement and impaired balance and coordination.
 
Henrik Wilms, M.D., a neurologist at Texas Tech Physicians, said the mean age of onset in Parkinson’s disease is 70.
 
“When someone is younger than 40 years of age like Errin, it is referred to as young onset Parkinson’s disease,” Wilms said. “Normally, a patient who is 40 also may have a different lifestyle or activity level like keeping up with younger children and employment.”
 
Wilms said the traditional drug therapies used for Parkinson’s disease patients have side effects that will not allow patients to conduct their normal activities.
 
“When you have Parkinson’s disease, the patient’s brain stops producing enough dopamine,” Wilms said. “Dopamine is the chemical that communicates with your nerves to coordinate movement and balance. Yet, as patients’ symptoms progress, more medication is needed causing sleepiness and dyskinesia (the jerking involuntary movements.)”
 
As Luton has dealt with the disease through the years, his life changed drastically. He quit his job, was unable to drive and symptoms continued to worsen.
 
“My life depended on medications,” Luton said. “I couldn’t balance. I had uncontrollable tremors, and I couldn’t do anything without assistance. My medications also started to cause dyskinesia. I was taking up to 16 pills a day.”
 
Wilms said Parkinson’s disease is a chronic and progressive disease with no cure.
 
“It’s about chasing the symptoms and trying to help each patient,” Wilms said. “In Errin’s case, he had been on drug treatments for about 6 or 7 years. I knew he might be a good candidate for deep brain stimulation. As a young resident my colleague told me about this procedure years ago. It is not new but has advanced throughout the years.”
 
Deep brain stimulation was introduced in 1990 and works by sending targeted stimulation signals to areas of the brain that cause the involuntary movements, using a pacemaker-like device. The electrodes produce electrical impulses to regulate a cluster of nerves that cause the tremors. The U.S. Food and Drug Administration approved deep brain stimulation for patients with Parkinson’s disease. Luton was a good candidate and in October 2017, underwent the procedure in San Angelo with neurosurgeon Luis Duarte, M.D.
 
“I am not going to lie,” Luton said. “The first two months after the surgery were hard. It is brain surgery and pain comes with that. Talking to Dr. Wilms about my symptoms at the time made this procedure the best option to go. It took about 6 weeks after I had the implant that my tremors stopped. After about a couple of weeks they returned but not as strong.”
 

Gradually with each visit, Luton’s symptoms have diminished. Wilms adjusts the Abbott Infinity™ Deep Brain Stimulation System devise at each appointment. The deep brain stimulation device streamlines the therapy with a wireless IOS software platform using an Apple iPad for programming. The physician is the only person who can adjust the device. As Wilms turns off the deep brain stimulator to adjust it, within seconds Luton’s tremors reappear.
 
“It is actually kind of crazy, but my brain is connected to an iPad,” Luton said. “Every time I have gone back to Dr. Wilms to adjust it, my tremors have lessened. I am at the point that I have no tremors on my right side. This visit was for him to make adjustments to help with tremors on my left arm.”
 
Wilms stresses this device is not for everyone. An ideal candidate must have good responses to the drug therapies for deep brain stimulation to work. Unfortunately, 20 years into the disease most patients also experience symptoms of impaired memory and concentration. If this has progressed into full-blown dementia, then the patient is not a good candidate. Some patients also suffer from depression and if it were an uncontrolled depression, the patient would not be a candidate for deep brain stimulation.
 
As Wilms turns back on the deep brain stimulation device from his iPad, Luton’s tremors slowly begin to stop again.
 
“We are watching miracles,” Wilms said.
 
Luton, who now lives in Borger, has now reduced his medications by 40 percent and is driving and getting back to activities Parkinson’s disease was keeping him from. He hopes to return to college and even plans on training to run a marathon.
“I feel a hundred percent better and even sleep most of the night,” Luton said. “My kids love it. They think it is great that I am a lot more active and got my movement that I had lost throughout the years. They joke that it is cool to have a bionic dad.”