Targeted Orphaned Domain May Lead to Drug Therapies for Nervous System Diseases and Inflammatory Processes
Research key to possible drug therapies for nervous system diseases and inflammatory processes
"We are especially interested in the superfamily of pentameric ligand-gated ion channels (pLGICs) that includes the nAChR, GABA, 5-HT3, and glycine families," Jansen said. "The pLGICs function mainly as neurotransmitter receptors, transforming the chemical signal contained in the neurotransmitter into an electrical signal."
The current therapies make it impossible to precisely hit one target because there are more than 40 different subunits in humans. All the drugs currently in clinical use, target the extracellular or transmembrane domains, which are structurally very similar across different subunits.
Read the full story here.
Related Stories
38th Student Research Week Successful at Showcasing Secrets of Immune Defense
Student researchers at TTUHSC had the opportunity to showcase their presentation skills at the 38th Annual Student Research Week Feb. 25 – 27.
Celebrating Veterans: TTUHSC’s General Martin Clay’s Legacy of Service and Leadership
From his initial enlistment in the Army National Guard 36 years ago to his leadership in military and civilian health care management roles, Major General Martin Clay’s career has been shaped by adaptability, mission focus and service to others.
Texas Tech University Health Sciences Center School of Nursing Named Best Accelerated Bachelor of Science in Nursing Program in Texas
The TTUHSC School of Nursing Accelerated Bachelor of Science in Nursing (BSN) program has been ranked the No. 1 accelerated nursing program in Texas by RegisteredNursing.org.
Recent Stories
TTUHSC Researchers Collaborate in Study of Cancer Drug’s Possible Positive Effects on Alzheimer’s Disease
A drug typically used to treat some forms of cancer may also help delay the progression of Alzheimer’s disease. Boris Decourt, Ph.D., director of the TTUHSC Laboratory on Neurodegeneration and Translational Research, is part of the Phase II trial.
TTU System Board of Regents Approves Appointment of Grover E. Murray Professor
The Texas Tech University System Board of Regents today (Aug. 13) approved the appointment of Rodney Young, M.D., from the Texas Tech University Health Sciences Center (TTUHSC) School of Medicine, as a Grover E. Murray Professor.
From Backpacks to White Coats
TTUHSC School of Medicine Admissions Office team members delivered critical school supplies worth nearly $6,500 in total on Thursday, Aug. 6, to Bayless Elementary School.