Did FDA Do Right by Cutting Acetaminophen Dose in Rx Products? - Anesthesiology News

Clinicians striving to provide patients with pain relief, without risking toxicity, received some support from federal officials in January, when the FDA recommended limiting the dose of acetaminophen to 325 mg in combined prescription products.

Charles Seifert, PharmD, FCCP, BCPS, described it as a thoughtful approach. “If you reduce the amount of acetaminophen in those products, that’s a really nice middle ground, if you will,” said Dr. Seifert, professor of pharmacy practice in the School of Pharmacy at Texas Tech University Health Sciences Center in Lubbock. “Now you can still get them as Schedule III. But you hope that, as you increase the narcotic component, the acetaminophen doesn’t exceed 4 g a day.” ...

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