New Research to Examine Effects of Vitamin E on Obesity

Leslie Shen, Ph.D., C.C.R.P

Of the 13 essential vitamins, vitamin E is known to benefit vision, reproduction and a person’s blood, brain and skin. Researchers at Texas Tech University Health Sciences Center (TTUHSC) now are studying vitamin E to examine the effects of the vitamin on obesity with obese adults.
Vitamin E has antioxidant properties that protect cells against molecules produced when your body breaks down food. Leslie Shen, Ph.D., C.C.R.P., a TTUHSC professor in the Department of Pathology, said these molecules may play a role in other diseases such as obesity.

“The presence of chronic low-grade inflammation in obese people plays an important role in the development of obesity- associated insulin resistance, diabetes and cardiovascular disease,” Shen said. “Among these risk factors, obesity is now recognized as a worldwide epidemic disease. Obesity-induced chronic low-grade inflammation is initiated by excess nutrients in metabolic cells.”

Shen said aging and the decline of estrogen are factors that contribute to weight gain in postmenopausal women, and approaches, such as anti-inflammatory potential in dietary antioxidants to reduce inflammation may likely combat obesity. TTUHSC researchers are conducting a 24-week research study examining the effects of tocotrienols, a type of vitamin E, on obesity-associated outcome measures in obese men and women.

Participants are needed for this study, “Effect of Tocotrienol (vitamin E isomers) on Obesity.” Shen said other studies have indicated tocotrienols supplements may be good for mitigating negative impacts of obesity in obese adults.

“However, no study has ever been done on the role of tocotrienols in obesity in adult men and women,” Shen said. “Our long-term goal is to develop a new strategy featuring a dietary supplement such as tocotrienols for mitigating negative impacts of obesity in adult men and women.”

Participants should be adult men and women. Participation is free of charge. The study is funded by a grant from School of Medicine, TTUHSC, the Laura W. Bush Institute for Women’s Health and American River Nutrition, L.L.C.  

For more information about this research study, contact the Clinical Research Institute at (806) 743-4471 or via email.

Leslie Shen, Ph.D., C.C.R.P.,

Related Stories

Research

Das Selected as Fellow by National Academy of Inventors

Hiranmoy Das, Ph.D., a professor of pharmaceutical sciences at the TTUHSC Jerry H. Hodge School of Pharmacy, has been named a Fellow of the National Academy of Inventors (NAI), the organization announced Dec. 10.

Research

TARCC, AHA Grants to Aide TTUHSC Researcher

Murali Vijayan, Ph.D., an assistant professor in the Department of Internal Medicine at TTUHSC, has been awarded a research grant from the Texas Alzheimer’s Research and Care Consortium to investigate the role of Voltage-Dependent Anion Channel 1 in Alzheimer’s disease.

Research

The Kenneth H. Cooper Institute at Texas Tech University Health Sciences Center Unveiled in Dallas

Today (Nov. 4) TTUHSC officially welcomed The Cooper Institute as part of its organization with a special presentation and unveiling of its new name – the Kenneth H. Cooper Institute at Texas Tech University Health Sciences Center.

Recent Stories

Health

The “Happiest” Time of the Year: Grief and the Holidays

David Pfaff, Ph.D., LPC, is core faculty for the Clinical Mental Health Counseling program at TTUHSC and discussed grief during the holidays.

Research

Das Selected as Fellow by National Academy of Inventors

Hiranmoy Das, Ph.D., a professor of pharmaceutical sciences at the TTUHSC Jerry H. Hodge School of Pharmacy, has been named a Fellow of the National Academy of Inventors (NAI), the organization announced Dec. 10.

Health

Navigating Family Stress During the Holiday Season

Nicole Noble, Ph.D., an assistant professor in the Clinical Mental Health Counseling Program, offered insights to help manage difficult family dynamics during this time of year.